ABNORMAL MECHANICAL STRESS ON BICUSPID AORTIC VALVE INDUCES VALVULAR CALCIFICATION AND INHIBITS NOTCH1/NICD/RUNX2 SIGNAL

Abnormal mechanical stress on bicuspid aortic valve induces valvular calcification and inhibits Notch1/NICD/Runx2 signal

Background Bicuspid aortic valve (BAV) is a congenital cardiac deformity, increasing the risk of developing calcific aortic valve disease transpharm online shopping (CAVD).The disturbance of hemodynamics can induce valvular calcification, but the mechanism has not been fully identified.Methods We constructed a finite element model (FEM) of the aort

read more

Intraoperative neurophysiologic monitoring alteration during en bloc laminectomy surgery for thoracic ossification of ligamentum flavum

BackgroundThere is real risk during en bloc resection for the treatment of thoracic ossification of ligamentum flavum (TOLF).Intraoperative neurophysiologic monitoring (IONM) has been applied to monitor neurologic functional integration of the spinal cord during surgery.However, the IONM outcome and its relationship with clinical results still need

read more

Lactiplantibacillus plantarum Postbiotics: Alternative of Antibiotic Growth Promoter to Ameliorate Gut Health in Broiler Chickens

The postbiotic produced from Lactiplantibacillus plantarum has been revealed as a potential alternative to antibiotic growth promoters (AGP).It helps to stimulate growth performance, improve nutrient digestibility, intestinal histomorphology, immune response, and improve meat quality in livestock.However, there is a paucity of information on the ef

read more